Diagnosis and management of this easily missed condition
- By: Bijay Vaidya, Ali J Chakera, Catherine Dick
Addison’s disease (also known as primary adrenal insufficiency) is a chronic disorder of the adrenal cortex resulting in inadequate secretion of glucocorticoid and mineralocorticoid. The commonest cause of Addison’s disease in developed countries is autoimmune disorder and in developing countries is tuberculosis.1
The onset of Addison’s disease is often insidious. Its usual symptoms (such as fatigue, lethargy, weakness, and low mood) are non-specific, are highly prevalent in the general population, and overlap with many other common conditions.