A cultured Nobel prize winner
In 1982 Barry Marshall and Robin Warren cultured Helicobacter pylori for the first time and defied conventional medical wisdom by declaring the bacteria the cause of most stomach ulcers. Marshall received the Lasker prize in 1995, the most coveted prize in US medicine, because “rarely do the discoveries of a single individual change the lives of countless millions within … a decade.” And in 2005 Marshall and Warren were awarded the Nobel prize for medicine. Today Marshall is a clinical professor at the University of Western Australia. Ronan W Glynn caught up with him
Science was what I was really interested in, and I thought about being a chemist. I was somewhat interested in medicine because my mother was a nurse, and I was exposed to some medical books at home, so I knew about anatomy and physiology. Later I became interested in internal medicine because it was challenging-it seemed to me there were a lot of specialties in medicine in which you could pretty much learn 99% in a few years, and after that they wouldn't be new any more. The research was an extra that we were encouraged to do as part of our internal medicine training, and that's how my interest in Helicobacterpylori started.
H pylori sits in your stomach, and your immune system sees it and reacts against all its antigens, so, there might be a way of producing vaccination by inserting new genes into H pylori. We know that